Radiotherapy Physics

Published papers

F Houghton, RJ Benson, GSJ Tudor, J Fairfoul, J Gemmill, JC Dean, DS Routsis, SJ Jefferies, NG Burnet “An Assessment of Action Levels in Imaging Strategies in Head and Neck Cancer using TomoTherapy. Are Our Margins Adequate in the Absence of Image Guidance?” Clin. Oncol 21 720-7(2009)

David Eaton, Nicola Twyman, Simon Thomas

“Commissioning a miniature multileaf collimator for small field radiotherapy”

Medical Dosimetry. Available online 09 February 2009

DOI: 10.1016/j.meddos.2008.12.002

Catharine H. Clark, Vibeke Nordmark Hansen, Hannah Chantler, Craig Edwards, Hayley V. James, Gareth Webster, Elizabeth A. Miles, M. Teresa Guerrero Urbano, Shree A. Bhide, A. Margaret Bidmead, Christoper M. Nutting. on behalf of the PARSPORT Trial Management Group Dosimetry audit for a multi-centre IMRT head and neck trial.

Radiother Oncol. 2009 Apr 26. [published online 14 July 2009]

Barnett GC, Wilkinson J, Moody AM, Wilson CB, Sharma R, Klager S, Hoole AC, Twyman N, Burnet NG, Coles CE.

A randomised controlled trial of forward-planned radiotherapy (IMRT) for early breast cancer: Baseline characteristics and dosimetry results

Radiother Oncol. 2009 Apr 16. [Epub ahead of print]

Nguyen TB, Hoole ACF, Burnet NG and Thomas SJ

The optimization of intensity modulated radiotherapy

in cases where the planning target volume extends into

the build-up region

Phys. Med. Biol. 54 (2009) 2511-2525

Nguyen TB, Hoole ACF, Burnet NG and Thomas SJ

Dose–volume population histogram: a new tool for evaluating plans whilst considering geometrical uncertainties

Phys. Med. Biol. 54 (2009) 935–947

Tan LT, Coles CE, Hart C, Tait E.

Clinical Impact of Computed Tomography-based Image-guided Brachytherapy for Cervix Cancer using the Tandem-ring Applicator - the Addenbrooke's Experience.

Clin Oncol (R Coll Radiol). 2009 Apr;21(3):175-82.

Thomas SJ, Eaton DJ, Tudor GSJ and Twyman NI. Equivalent squares for small field dosimetry. .  Br J Radiol.81 (2008) 897-901

Rimmer YL, Burnet NG, Routsis DS, Twyman N,  Hoole ACF, Treeby J, Welford D, Fairfoul J, 'Aho T, Vowler SL, Benson RJ.

Practical issues in the implementation of image-guided radiotherapy for the treatment of prostate cancer within a UK department.

Clin Oncol (R Coll Radiol). 2008 Feb;20(1):22-30.

Tudor GSJ “Comparison of rectal dose histograms under conditions of nonlinear isodoses” Physics in Medicine and Biology 2007; 52, 275-289

Coles CE, Cash CJC, Treece GM, Miller NAC, Hoole ACF, Gee AH, Prager RW, Sinnatamby R, Britton P, Wilkinson JD, Puroshotham AD and Burnet NG.  High definition three dimensional ultrasound to localize the tumour bed: A breast radiotherapy planning study. 

Radiotherapy and Oncology 2007;  84, 233-241

Abstracts

TB Nguyen, AFC Hoole, NG Burnet, and SJ Thomas

Incorporating Geometric Uncertainties Into IMRT Optimisation for Prostate Cases Using a Multiple Isocenter CTV-Based (miCTV-Based) Objective Function 

Med. Phys. 36 2562 (2009)

TB Nguyen, AFC Hoole, NG Burnet, and SJ Thomas

A New Method to Calculate the Dose Distribution From An Isocenter Shift Without Recalculating Dose Distribution to Evaluate Plan with Geometric Uncertainties 

Med. Phys. 36 2663 (2009)

Tudor GS, Lane J, Thomas SJ, Tait EE, Chantler HJ, Barachlough J, Carroll HE “Effect of respiratory motion on tomotherapy, step-and-shoot IMRT and conformal radiotherapy treatments” . Presented at IPEM national meeting “Managing Motion in Radiotherapy (2009)

Coles CE, Barnett GC, Wilkinson J, Moody AM, Wilson CB, Twyman N, Hoole ACF, Burnet NG, Wishart GC.

A randomised controlled trial of forward-planned Intensity Modulated Radiotherapy (IMRT) for early breast cancer: interim results at 2 years follow-up for Presentation at the 32nd Annual San Antonio Breast Cancer Symposium, December 9 - 13, 2009 in San Antonio, Texas.

Thomas SJ, Vinall A, Poynter A and Routsis D, A multi-centre timing study of IMRT planning and delivery.  IPEM MPEC, Liverpool September 2009, (abstract book ISBN 978-1-903613-37-5, pp70-71)

Barraclough J, Whitney D and Hart C. The commissioning of 3D image guided brachytherapy for Iridium wire treatments.  IPEM MPEC, Liverpool September 2009, (abstract book ISBN 978-1-903613-37-5, p45)

Cowen MA, Williams MV, Horan G and Thomas SJ.  Inclusion of predicted carcinogenic risks in treatment plan optimisation.

IPEM MPEC, Liverpool September 2009, (abstract book ISBN 978-1-903613-37-5, p80)

Thomas SJ, Nguyen TB, Cowen M, Lenane M, Rimmer Y and Burnet NG.  The effect of geometric uncertainties on population TCP for multiple-phase prostate radiotherapy.  ESTRO, Gotteberg, September 2008.

Coles CE, Wilkinson JS, Wilson CB, Burnet NG, Twyman N, Hoole ACF, GC Wishart, Moody AM The Cambridge Breast Intensity Modulated Radiotherapy (IMRT) Trial: Dosimetry results. Poster. San Antonio, December 2007 and Presentation Breast cancer campaign conference. Spring 2008.

Carroll HE and Twyman N. Audit of image quality and geometrical accuracy of digitally reconstructed radiographs from different treatment planning systems. IPEM Biennial Radiotherapy Meeting.  Bath. September 2008

Adams EJ., Fairfoul J, Routsis D, Dean J, Thomas SJ and Burnet NG.  Implementation and initial experience of Tomotherapy.   IPEM Biennial Radiotherapy Meeting.  Bath. September 2008

Set up accuracy measured with 6 degrees of freedom (dof) information for pelvic radiotherapy using tomotherapy on-line image registration D. Routsis, J. Dean, R. Kirby, L. Adams, J. Fairfoul, S. Thomas, S.

Russell, H. Patterson, Y. Rimmer, N. Burnet.  ESTRO, Gotteberg, September 2008

Evaluation of tumour bed localisation and image-guided radiotherapy for breast cancer: the import gold seed study C. Coles, G. Wishart, J. Wilkinson, S. Vowler, J. Vasconcelos, E.Donovan, J. Fairfoul, E. Harris, C. Mackenzie, D. Routsis, A. Poynter, C. Rawlings, N.Twyman, R. Wilks, J. R. Yarnold.  ESTRO, Gotteberg, September 2008

Image-guided radiotherapy (IGRT) for prostate cancer: effect of residual set-up errors and intra-fractional motion on planning target volume (PTV) margins. R. Benson,Y. Rimmer, S. Tudor, J. Dean, N. Muskett, H. Patterson, S. Russell, C. Woodward, J. Fairfoul, A. Doble, N. Burnet ESTRO, Gotteberg, September 2008

The use of a dietary protocol - is there any benefit in prostate radiotherapy with or without image-guidance? Y. Rimmer, R. Benson, A. Lynch, J. Treeby, D. Routsis, J. Fairfoul, A.Hoole, A. Doble, N. Burnet  ESTRO, Gotteberg, September 2008

The import high planning study: defining dose constraints and treatment planning methods for complex breast radiotherapy H. James, L. Ciurlionis, C. Coles, E. Donovan, H. Mayles, Y. Tsang, N. Twyman, J. R. Yarnold.  ESTRO, Gotteberg, September 2008

IMRT plan optimisation for skullbase lesions: planning class solutions. V. J. Estall, N. Burnet, R. Jena, D. Eaton.  ESTRO, Gotteberg, September 2008

D. Routsis, J. Fairfoul, Y. Rimmer, J. Dean, N. Muskett, M. Akhtar, N.Burnet, R. Benson

Identification of implanted fiducial markers- Does increased portal imaging (PI ) dose improve inter-observer variability? 9th biennial ESTRO meeting on physics

and radiation technology for clinical radiotherapy September, 2007 Barcelona, SPAIN

TB Nguyen, SJ Thomas, ACF Hoole, and NG Burnet

IMRT Optimization Using a Shifted CTV-Based Objective Function 

Med. Phys. 34 2460 (2007)

C.E. Coles, G.C. Wishart, J. Fairfoul, E. Donovan, E. Harris, A. Poynter, J.S. Wilkinson, S. Tudor, J. Yarnold : on behalf of the IMPORT Trial Management Group. “Implanted gold seeds for tumour bed localisation and image-guided radiotherapy”  European Journal of Cancer Supplements 5(3) O-17 (Sep 2007)

Invited Presentations

Thomas SJ.  Impact of New Technologies on Bunker Design.  IPEM Meeting on “Current developments in the design of radiotherapoy treatment room facilities” London 18th March 2009.

Thomas SJ.  Teaching lecture on “Radiotherapy Treatment Planning Algorithms”. IPEM Biennial Radiotherapy Meeting.  Bath. September 2008

Adams E. Implementation of TomoTherapy within an NHS department BIR meeting on Tomographic Image Guided Radiotherapy. London November 2007