Addenbrooke's Hospital
Research and Development
The Rosie Hospital
Box: 152
Cambridge University Hospitals NHS Foundation Trust
Hills Road,
Cambridge,
CB2 0QQ
Enquiries: 01223 216 472
Fax: 01223 257 137
Treatment equipment supported | Planning systems | Imaging systems | Areas of interest | Courses | Recent publications | PhD projects
Radiotherapy Physics provides a comprehensive Physics service to the Addenbrooke’s Radiotherapy Centre ensuring the safe and accurate use of high dose ionising radiation to treat patients with cancer, whilst maintaining a safe environment for other patients, visitors and staff.
Physicists, technicians and radiographers work closely with Oncology staff to provide a wide range of scientific and technical advice and support for all radiotherapy treatments. Routine clinical work includes radiotherapy treatment planning and related dosimetry the provision of brachytherapy, and the manufacture of immobilisation and shielding equipment for patients. Extensive support is provided to radiotherapy equipment. This incorporates the design of facilities; the management of computer systems, the design and management of software; and the commissioning, servicing and quality control of Linear Accelerators, Orthovoltage units, Brachytherapy units and CT scanners. All our work and related dosimetry are monitored and assured to nationally and internationally agreed specifications and legal requirements.
We are involved in research and development in radiotherapy physics, and have PhD students from the University of Cambridge based in our department.
We are also responsible for providing radiotherapy physics advice and support to two University Departments (Veterinary Medicine and Pathology).
Treatment equipment supported
Linacs:
Other equipment:
Planning systems
Imaging systems
Areas of interest
Courses
Fundamentals of Radiotherapy Planning
This course has been run since 2000. The last one was run in November 2010. The next one is provisionally scheduled for 21-23 November 2011, at the Moller Centre in Cambridge. Further details, when available, will be on the RCR web site.
Recent publications
Authors from Addenbrooke’s
Radiotherapy Physics are underlined
Published papers |
Loo H, Fairfoul J, Chakrabarti A, Dean JC, Benson RJ, Jefferies SJ, Burnet NG. Tumour Shrinkage and Contour Change during Radiotherapy Increase the Dose to Organs at Risk but not the Target Volumes for Head and Neck Cancer Patients Treated on the TomoTherapy HiArt(TM) System. Clin Oncol (R Coll Radiol). 2010 Oct 5. [Epub ahead of print] |
Thomas SJ, Vinall A, Poynter A, Routsis D. A Multicentre Timing Study of Intensity-modulated Radiotherapy Planning and Delivery. Clin Oncol (R Coll Radiol). 2010 Oct;22(8):658-65. |
Estall V, Fairfoul J, Jena R, Jefferies SJ, Burton KE, Burnet NG. |
Donovan EM, Cuirlionis L, Fairfoul J, James H, Mayles H, Manktelow S, Raj S, Tsang Y, Tywman N, Yarnold J, Coles C |
Eaton D, Twyman N, Thomas S Commissioning a miniature multileaf collimator for small field radiotherapy. Med Dosim. 2010 Spring;35(1):1-6. |
Estall VJ, Eaton D, Burton KE, Jefferies SJ, Jena R, Burnet NG Intensity-modulated radiotherapy plan optimisation for skull base lesions: practical class solutions for dose escalation. |
Burnet NG, Adams EJ, Fairfoul J, Tudor GS, Hoole AC, Routsis DS, Dean JC, Kirby RD, Cowen M, Russell SG, Rimmer YL, Thomas SJ. |
Williams MV, Hoole AC, Dean JC, Russell SG, Thomas SJ, Fairfoul J, Burnet NG. |
Jena R, Kirkby NF, Burton KE, Hoole AC, Tan LT, Burnet NG. |
Houghton F, Benson RJ, Tudor GS, Fairfoul J, Gemmill J, Dean JC, Routsis DS, Jefferies SJ, Burnet NG. |
Clark CH, Hansen VN, Chantler H, Edwards C, James HV, Webster G, Miles EA, Guerrero Urbano MT, Bhide SA, Bidmead AM, Nutting CM; PARSPORT Trial Management Group. |
Barnett GC, Wilkinson J, Moody AM, Wilson CB, Sharma R, Klager S, Hoole AC, Twyman N, Burnet NG, Coles CE. |
Nguyen TB, HooleACF, Burnet NG and Thomas SJ |
Nguyen TB, HooleACF, Burnet NG and Thomas SJ |
Tan LT, Coles CE, Hart C, Tait E. |
Thomas SJ, Eaton DJ, Tudor GSJ and Twyman NI. Equivalent squares for small field dosimetry. . Br J Radiol.81 (2008) 897-901 |
Rimmer YL, Burnet NG, Routsis DS, Twyman N, Hoole ACF, Treeby J, Welford D, Fairfoul J, 'Aho T, Vowler SL, Benson RJ.
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Presentations/Posters |
D. O’Doherty, L. Tait & J. Fairfoul, Delta4 and Tomotherapy – Our Experience, presentation, IPEM Biennial Radiotherapy meeting, Cardiff July 2010 |
Barraclough, J.M., Chantler, H. J. & Geater, A. 2010, Dosimetric effects of high density valves in breast radiotherapy treatment planning, IPEM Annual Scientific Meeting, Cardiff, poster presentation |
M Cowen*, MV Williams, G Horan, M Mukesh and SJ Thomas “Potential benefits and risks in treating paediatric neuroblastoma patients with IMRT using helical tomotherapy”, ESTRO, Barcelona, September 2010 |
S Loo*, G Horan, J Fairfoul, S Tudor, M Lenane, J Dean, M Cowen, S Thomas, N Burnet and M Williams "Craniospinal radiotherapy using helical tomotherapy for paediatric medulloblastoma: developing dose constraints", ESTRO, Barcelona, September 2010 |
Eyre K and Thomas SJ. Comparison of image registration packages for use in radiotherapy planning. IPEM Biennial Radiotherapy meeting,Cardiff University, 6-7 July 2010 |
M Cowen* and SJ Thomas “Monte Carlo modelling the effect of translational shifts and rotations on prostate dose-population histograms - what margins are required for IGRT?” AAPM, Philadelphia, July 2010 |
Chantler H. Advances in the radiotherapy of head & neck cancer: The Addenbrookes experience. Head & Neck cancer: advances in radiation treatment meeting, London, 30 April 2010 |
Barraclough, J.M., Whitney, D. & Brooke, S. 2009, The Commissioning of 3D Image Guided Brachytherapy for Iridium Wire Treatments, IPEM Brachytherapy in the Modern Era, Manchester, poster presentation |
Barraclough, J.M. 2009, The Commissioning of 3D Image Guided Brachytherapy for Iridium Wire Treatments, IPEM Annual Scientific Meeting, Liverpool, oral presentation |
Cowen MA*, Williams MV, Horan G and Thomas SJ. “Inclusion of predicted carcinogenic risks in treatment plan optimisation” IPEM MPEC, Liverpool September 2009, (abstract book ISBN 978-1-903613-37-5, p80) |
Thomas SJ, Nguyen TB, Cowen M, Lenane M, Rimmer Y and Burnet NG. The effect of geometric uncertainties on population TCP for multiple-phase prostate radiotherapy. ESTRO, Gotteberg, September 2008. |
Adams EJ., Fairfoul J, Routsis D, Dean J, Thomas SJ and Burnet NG. Implementation and initial experience of Tomotherapy. IPEM Biennial Radiotherapy Meeting. Bath. September 2008 |
Set up accuracy measured with 6 degrees of freedom (dof) information for pelvic radiotherapy using tomotherapy on-line image registration D. Routsis, J. Dean, R. Kirby, L. Adams, J. Fairfoul, S. Thomas, S. |
Evaluation of tumour bed localisation and image-guided radiotherapy for breast cancer: the import gold seed study C. Coles, G. Wishart, J. Wilkinson, S. Vowler, J. Vasconcelos, E.Donovan, J. Fairfoul, E. Harris, C. Mackenzie, D. Routsis, A. Poynter, C. Rawlings, N.Twyman, R. Wilks, J. R. Yarnold. ESTRO, Gotteberg, September 2008 |
Image-guided radiotherapy (IGRT) for prostate cancer: effect of residual set-up errors and intra-fractional motion on planning target volume (PTV) margins. R. Benson,Y. Rimmer, S. Tudor, J. Dean, N. Muskett, H. Patterson, S. Russell, C. Woodward, J. Fairfoul, A. Doble, N. Burnet ESTRO, Gotteberg, September 2008 |
The use of a dietary protocol - is there any benefit in prostate radiotherapy with or without image-guidance? Y. Rimmer, R. Benson, A. Lynch, J. Treeby, D. Routsis, J. Fairfoul, A.Hoole, A. Doble, N. Burnet ESTRO, Gotteberg, September 2008 |
The import high planning study: defining dose constraints and treatment planning methods for complex breast radiotherapy H. James, L. Ciurlionis, C. Coles, E. Donovan, H. Mayles, Y. Tsang, N. Twyman, J. R. Yarnold. ESTRO, Gotteberg, September 2008 |
IMRT plan optimisation for skullbase lesions: planning class solutions. V. J. Estall, N. Burnet, R. Jena, D. Eaton. ESTRO, Gotteberg, September 2008 |
Coles CE, Wilkinson JS, Wilson CB, Burnet NG, Twyman N, Hoole ACF, GC Wishart, Moody AM The Cambridge Breast Intensity Modulated Radiotherapy (IMRT) Trial: Dosimetry results. Poster. San Antonio, December 2007 and Presentation Breast cancer campaign conference. Spring 2008. |
Carroll HE and Twyman N. Audit of image quality and geometrical accuracy of digitally reconstructed radiographs from different treatment planning systems. IPEM Biennial Radiotherapy Meeting. Bath. September 2008 |
Whitney DM Implementing IGBT for Cervix Brachytherapy, IPEM Brachytherapy The Modern Era, Manchester, 24th Nov 2009 |
Whitney DM Dose Optimisation, IPEM Brachytherapy The Modern Era, Manchester, 24th Nov 2009 |
Whitney DM Physics Resources for IGBT for Cervix Brachytherapy, IPEM Brachytherapy The Modern Era, Manchester, 24th Nov 2009, Poster presentation. |
Barraclough, J.M., Whitney DM The commissioning of 3D Image Guided Brachytherapy for iridium wire treatments, IPEM Brachytherapy The Modern Era, Manchester, 24th Nov 2009, Poster presentation.
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Invited Presentations |
Whitney DM, The Advantages of Image Guided Brachytherapy of the Cervix, Brit Institute of Radiol., London 13th Oct 2010 |
Whitney DM, Implementation of Oncentra GYN for 3D Image Guided Brachytherapy of the Cervix, Nucletron Brachytherapy User Meeting, Liverpool, 21st May 2010 |
Thomas SJ. Impact of New Technologies on Bunker Design. IPEM Meeting on “Current developments in the design of radiotherapy treatment room facilities” London 18th March 2009. |
Thomas SJ. Teaching lecture on “Radiotherapy Treatment Planning Algorithms”. IPEM Biennial Radiotherapy Meeting. Bath. September 2008 |
PhD projects
Ian Cowley.
“New approaches to improving the accuracy and outcome of Intensity Modulated Radiotherapy.”
PhD awarded by the Open University 2006.
Supervisors: Simon Thomas, Philip Dendy, Sarah Brooke.
Thai-Binh Nguyen.
“Method of IMRT optimization of shallow tumour cases where the PTV extends into the build-up region”.
PhD awarded by the University of Cambridge 2009.
Supervisors: Neil Burnet, Simon Thomas, Andrew Hoole
Mark Cowen - “Image Guided Radiotherapy Using Tomotherapy”.
Due to complete 2011.
Funded by MRC studentship.
Sam Tudor - “Ensuring dosimetric coverage of radiotherapy treatment volumes”.
Commenced October 2009.
Part time PhD, supported by East of England SHA.
(Both with University of Cambridge, Department of Oncology. Supervisor: Simon Thomas)
Contact us:
Enquiries: 01223 216 472
Fax: 01223 257 137
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On other sites:
> NHS Trainee Clinical Scientist Recruitment
Information for Part I Clinical Scientist Training in Medical Physics & Clinical Engineering at Addenbrooke’s.