Diabetes, obesity and metabolic disorders

We will:

• build on research in monogenic and polygenic obesity to identify biomarkers for use in intervention studies and inform neuro-imaging studies;

 

• characterise known and novel genetic and metabolic disorders associated with type 2 diabetes with a view to developing new therapies;

 

• identify and implement novel approaches to improving control of type 1 diabetes in children and adults;

 

• evaluate novel therapies, including gene therapy, for inherited metabolic diseases;

 

• and use psychometric measures to determine how disorders of sexual development influence assessment and treatment of psychological status.