Genetics

 

 

 

We will develop:

1. programmes in renal genetic and tubular disorders and Huntington disease to identify causal biomarkers of diseases, using genetics to direct experiments and interpret results in genotype-selected subjects and identify therapeutic targets that lie in causal pathways.

 

2. The world-leading programme in type 1 diabetes is identifying therapeutic targets and prognostic biomarkers for disease prevention, through the development and use of the Cambridge BioResource, a panel of over 4,000 healthy donors that can be recalled by disease-associated genotypes.

 

3. A comprehensive understanding of the molecular genetics of X-linked mental retardation will be translated into the provision of rapid and effective diagnostic testing for patients and their families.